These columns utilise a unique silica-based, mixed-mode stationary phase that combines both reversed phase (RP) and hydrophilic interaction liquid chromatography (HILIC) properties. The column's functional group features a hydrophobic alkyl chain and hydrophilic diol functionality. This combination allows both hydrophobic interaction and hydrophilic interaction to be utilised to optimise separations.
- Retains highly polar molecules
- Unique selectivity complementary to RP columns
- Superior performance compared to conventional diol-based columns
Suitable for separation of both polar and non polar molecules with selectivity complementary to RP columns and suitable for a broad range of applications, including drug metabolites, lipids, polyethylene glycols (PEGs), ethoxylated surfactants and more.
Particle type: High purity, spherical silica
Flow rate range: 0,2 to 0,5 ml/min for 2,1 mm ID formats; 0,4 to 1,0 ml/min for 3,0 mm ID formats; 0,8 to 2,0 ml/min for 4,6 mm ID formats