United Kingdom
Order Entry
Anti-MAP3K4/MEK kinase-4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
  BOSSBS-11883R-A680
 :  Bioss
Anti-MAP3K4/MEK kinase-4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
  BOSSBS-11883R-A680
 :  Bioss
 
£835.00
   
  1 * 100 µl

 

  • Antibody type:
    Primary
  • Antigen name:
    MAP3K4/MEK kinase-4
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
  • Environmentally Preferable:
  • Epitope:
    1351-1450/1608
  • Form:
    Liquid
  • Antigen synonyms:
    M3K4_HUMAN|MAP3K4|FLJ42439|Mitogen-activated protein kinase kinase kinase 4|MAPK/ERK kinase kinase 4|KIAA0213|MTK1|MEKK4|PRO0412|MEKK 4|MAP three kinase 1|MAPKKK4 antibodyMEK kinase 4|RP3-473J16.4
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    182 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human MAP3K4/MEK kinase-4
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

 

 

Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK path-way. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.

Type: Primary
Antigen: MAP3K4/MEK kinase-4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 1351-1450/1608
Host: Rabbit
Isotype: IgG
Reactivity: