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Anti-CD28 Mouse monoclonal antibody unconjugated [clone: CD28.2]

Supplier: Tonbo Biosciences
The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

Type: Primary
Antigen: CD28 (CD28 molecule)
Clonality: monoclonal
Clone: CD28.2
Conjugation: unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity:




 

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Size Pk VWR Catalog Number Quantity
100 µg 100 µG 40-0289-U100
500 µg 500 µG 40-0289-U500
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SPECIFICATIONS

Antigen symbol CD28
Antigen name CD28 Molecule
Reactivity Macaque, Cynomolgus Monkey, Chimpanzee, Human, Baboon Macaque, Chimpanzee, Baboon, Cynomolgus Monkey, Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone CD28.2
Host Mouse
Isotype IgG1 kappa
ImmunoChemistry Yes
ImmunoPrecipitation Yes
Flow cytometry Yes
Antigen synonyms Tp44, T-cell-specific surface glycoprotein CD28, MGC138290, CD28 antigen MGC138290, CD28 antigen, T-cell-specific surface glycoprotein CD28, Tp44
Gene ID 940
Cross adsorption none
Storage temperature Cool
Shipping temperature Ice

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