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Normalisation & Purification Utilising Magnetic Beads

Normalisation & Purification Utilising Magnetic Beads

Many high-throughput applications, such as Next Generation Sequencing, Sanger Sequencing and genotyping, require the input DNA concentration to be within a certain range for optimal results. However, DNA prepared from multiple sources or extracted from different batches very often will have considerable variability in quantity and quality. Traditionally, a tedious process of quantification, calculation and concentration adjustment must be carried out to normalize the DNA samples.

Omega Bio-tek produces the Mag Bind® Normalizer Kit which simultaneously purifies and normalizes DNA concentrations without the need for quantification. Utilizing specially formulated magnetic beads that have a limited binding capacity, concentrations DNA can be adjusted by simply altering elution volumes