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VWR software solutions, providing support from validation to method optimisation and more

VWR software solutions, providing support from validation to method optimisation and more
  • Validation Manager - the quick and reliable way to validate analytical methods
  • ChromSword® Auto software for fully automatic HPLC method optimisation
  • ChromSword® software - for computer-assisted HPLC method optimisation
  • AutoRobust software - simple programming and automatic HPLC  robustness testing

Validation Manager - the quick and reliable way to validate analytical methods

Save time in the lab and improve your methods with this unique VWR International software tool  

  • Based on international guidelines for method validation
  • Versatile configuration for all analytical techniques
  • Easy operation and data entry
  • Automatic calculation and evaluation of the method characteristics
  • Automatic report compilation
  • Validated and fully FDA compliant

When operating according to quality management systems (e.g. according to GMP, GLP or ISO guidelines), validation of procedures used is of the utmost importance. However, this process, including the compilation of the validation report, is often tedious and time-consuming. Validation Manager is a valuable, timesaving aid, that checks whether your analytical methods are suitable for the intended use and automatically produces the validation report you need. As a comprehensive tool for method validation Validation Manager supports the user in the different steps of the validation procedure. Substantial time savings can be realised especially by the automatic compilation of the validation report. If you are interested in a free demo of this software via Webex/Internet, please register online. We’ll inform you on the available dates.

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ChromSword Auto® software for fully automatic HPLC method optimisation

Save time in the lab and improve your methods with this unique VWR International software tool

  • Separation of more substances and also with lowest concentrations of impurities (> 50 peaks, < 0.05 %)
  • Better peak resolution - higher degree of robustness and more reliable
  • Faster separations, shorter analysis times
  • Save time and effort in method development (fully automatic, optimisation overnight)
  • Savings of solvents in method development and routine analysis (cost, disposal, protection of the environment)
  • Gradual write-off of software costs after only a few method optimisation runs
  • Compatible with VWR-Hitachi, Agilent, Waters, Thermo-Dionex and Knauer HPLC systems

The unique ChromSword Auto®  software is capable of developing and optimising HPLC methods automatically within just a few hours. Methods already in use can also be optimised reducing analysis time considerably. All you have to do is place the sample in the autosampler, set a few parameters and start the optimisation process. ChromSword Auto®  then predicts the method conditions and controls the HPLC system connected in recording the chromatograms. These are analysed by the software and the optimal conditions determined. The Rapid Optimisation mode can be used to provide an overview of the performance of the column/solvent system selected or to rapidly screen columns and eluents considered for use. The Fine Optimisation mode additionally collects and evaluates further ancillary data and produces up to 10 sets of alternative optimal HPLC conditions. Both of these operating modes can be applied in combination with column and solving switching procedures in order to try a variety of column/solvent combinations or to establish optimal pH conditions – fully automatically. If you are interested in a free demo of this software via Webex/Internet, please register online. We’ll inform you of the available dates.

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ChromSword® software - for computer-assisted HPLC method optimisation

Save time in the lab and improve your methods with this unique VWR International software tool

ChromSword® is a unique and proven software system for computer-assisted HPLC method development and optimisation. This software enables chromatographic separations to be optimised virtually using physical-chemical retention models or empirically using real HPLC data. This is done by using various intelligent optimisation and simulation procedures with the optimisation objective of optimum peak resolution at minimum analysis time. On entering the structural formulae of the analytes under investigation, ChromSword predicts the best possible column/solvent combination and the optimal separation conditions for the analysis in question. The major advantage of this is that the subsequent method optimisation procedure already starts at the theoretically predicted optimum so that the number of chromatographic experiments is reduced to a minimum. If you are interested in a free demo of this software via Webex/Internet, please register online under or contact your VWR HPLC specialist. We’ll inform you of the available dates.

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AutoRobust software - simple programming and automatic HPLC robustness testing

Save time in the lab and improve your methods with this unique VWR International software tool

  • Very easy programming of the experimental matrix for robustness studies
  • Automatic performance of complete robustness study
  • Saves considerable time in the HPLC method development lab
  • Helps to improve the quality of your HPLC methods
  • Compatible with VWR-Hitachi, Agilent, Waters, Thermo-Dionex and Knauer HPLC systems

Robustness testing should be carried out for newly developed or existing analytical methods in order to establish the tolerance limits for minor deviations in method parameters. These should then be indicated in the corresponding analytical procedures (method SOPs). AutoRobust software can be used to rapidly programme the matrix for HPLC experiments to be carried out; the robustness tests are subsequently performed automatically. The software controls the HPLC system and records the chromatograms including any minor variations specified in the HPLC conditions. The chromatograms recorded and the corresponding peak parameters, e.g. peak resolution, are displayed. The software also produces a clearly arranged robustness test report.  If you are interested in a free demo of this software via Webex/Internet, please register online. We’ll inform you of the available dates.

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