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Upstream Processing

Upstream Processing

Enabling your scale up with the right products and quality requirements

Whether your expressions system is prokaryotic (bacteria) or eukaryotic (mammalian, yeast) the biochemicals and supplements we provide to grow organisms meet required quality and performance parameters that allows seamless transfer from R&D, to pilot scale and unto manufacture scale. Further, as you scale-up your process our supply chain management system can easily address increased quantities of material. Once the expression system has been determined and you investigate the growth media and feeds required to achieve maximum cell density and productivity, look to VWR to manufacture your in-house developed formulation either at our GMP facilities or on site at your location.

If your pilot scale or manufacturing facilities have been designed to accommodate single-use technologies, we provide state-of-the art mixing vessels, liquid holding and dispensing bags, and custom assembled sterile tubing and connectors designed to deliver fluid from mixing vessels to your seed bioreactors, then to the production scale bioreactor, and onto equipment used for protein capture, clarification, and concentration.

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