Dissolution testing

Dissolution media preparation can be a time consuming task when done manually. J.T.Baker® DILUT-IT™ dissolution media concentrates are pre-mixed concentrates that significantly reduce the amount of time and expense required to prepare dissolution media. This while also improving the quality and consistency of the media produced, which ultimately reduced rework and simplifies the task of regulatory compliance.

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Dissolution media concentrates

J.T.Baker® brand DILUT-IT™ are pre-measured and only need to be diluted with purified water to create a ready to use dissolution media, reducing the average preparation time by more than 75%.

FAQ

J.T.Baker® DILUT-IT™ dissolution media concentrates are pre-mixed concentrates that significantly reduce the amount of time and expense required to prepare dissolution media, while also improving the quality and consistency of the media produced, which ultimately reduces rework, and simplifies the task of regulatory compliance.

Simply pour the pre-mixed concentrate into a mixing chamber and add purified water to dilute to the appropriate volume depending on amount of media required (6 L, 25 L, or 50 L).

J.T.Baker® DILUT-IT™ dissolution media concentrates must be mixed with purified water for approximately 5 minutes. This mixing time is much shorter than traditional in-house dissolution media mixing processes, improving lab productivity.

Like laboratory prepared dissolution medias, J.T.Baker® DILUT-IT™ dissolution media concentrates should be used within 24 hours of mixing.

  • 230.8 mL of J.T.Baker® DILUT-IT™ dissolution media concentrate produces 6 L of diluted solution media;
  • 400 mL of J.T.Baker® SLS 0.50% DILUT-IT™ media concentrate produces 6 L of diluted solution media;
  • 961.5 mL of J.T.Baker® DILUT-IT™ dissolution media concentrate produces 25 L of diluted solution media;
  • 1.9 L of J.T.Baker® DILUT-IT™ dissolution media concentrate produces 50 L of diluted solution media.

J.T.Baker® DILUT-IT™ dissolution media concentrates are produced in Avantor’s ISO registered facilities, ensuring lot-to-lot consistency, reproducibility of results, and measurement of each batch against published product specifications.

J.T.Baker® DILUT-IT™ dissolution media concentrates are produced using raw materials in accordance with USP guidelines.

J.T.Baker® DILUT-IT™ dissolution media concentrates are packaged to stringent fill tolerances of ± 0.5% of target volume.

J.T.Baker® DILUT-IT™ dissolution media concentrates eliminate the need to store excess chemicals for time-consuming, in-house preparation of dissolution solutions.

  • Using J.T.Baker® DILUT-IT™ dissolution media concentrates greatly reduces the time required to prepare media in-house, enabling cost savings and improved productivity in the lab.
  • Reduced storage space requirements, along with lower freight charges make J.T.Baker® DILUT-IT™ a smarter choice than using traditional pre-mixed dissolution solutions in larger containers and bulky drums.
  • J.T.Baker® DILUT-IT™ dissolution media concentrates are suitable for all applications that require the use of dissolution media.
  • Smaller package sizes are offered for research and small batch applications, while larger sizes are ideal for use in Quality Control departments.

J.T.Baker® DILUT-IT™ dissolution media concentrates should be stored at room temperature.

J.T.Baker® DILUT-IT™ dissolution media concentrates are usable even if frozen. Simply let the media thaw at room temperature and use as normal when it has fully returned to a liquid state.

J.T.Baker® DILUT-IT™ dissolution media concentrates are packaged in high-density polyethylene bottles (HDPE) for enhanced safety.

J.T.Baker® DILUT-IT™ dissolution media concentrates provide increased productivity and cost savings for laboratory analysts/chemists performing dissolution testing because they eliminate many of the time-consuming steps which are typically associated with solution preparation.

Samples are available in the 230.8 mL size. Please contact your local distributor or sales representative to request a sample.

J.T.Baker® DILUT-IT™ dissolution media concentrates are offered in convenient packaging configurations and require minimal storage capacity. The 230.8 mL size and the 400 mL sizes of SLS 0.50% are available in cases of 12, while larger size concentrates (961.5 mL and 1.9 L) are available in cases of 6.

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